منابع مشابه
Chromatin dynamics
*Correspondence to: Craig L Peterson; Email: [email protected] Submitted: 06/03/2013; Accepted: 06/03/2013 http://dx.doi.org/10.4161/cc.25704 Comment on: Watanabe S, et al. Science 2013; 340:195-9; PMID:23580526; http://dx.doi.org/10.1126/science.1229758 Organization of eukaryotic genomes into compact, nucleoprotein fibers is key for stuffing a lot of DNA into a tiny nucleus, but thes...
متن کاملChromatin dynamics.
The expression patterns of many protein-coding genes are orchestrated in response to exogenous stimuli, as well as cell-type-specific developmental programs. In recent years, researchers have shown that dynamic chromatin movements and interactions in the nucleus play a crucial role in gene regulation. In this review, we highlight our current understanding of the organization of chromatin in the...
متن کاملEpigenomics and chromatin dynamics
and Chromatin Dynamics was one of the largest Keystone meetings to date, reflecting the excitement and many developments in this area. Richard Young opened the meeting by giving a historic overview before sharing more detailed insights from his recent work in describing the role of the lysine demethylase Lsd1 in mouse embryonic stem (ES) cell differentiation. He also set the broader stage and h...
متن کاملChromatin Dynamics in silicio
c © 2007 by John von Neumann Institute for Computing Permission to make digital or hard copies of portions of this work for personal or classroom use is granted provided that the copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. To copy otherwise requires prior specific permission by the publisher ment...
متن کاملChromatin Dynamics and Gene Positioning
The mammalian cell nucleus provides a landscape where genes are regulated through their organization and association with freely diffusing proteins and nuclear domains. In many cases, specific genes are highly dynamic, and the principles governing their movements and interchromosomal interactions are currently under intensive study. Recent investigations have implicated actin and myosin in chro...
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ژورنال
عنوان ژورنال: Annual Review of Biophysics
سال: 2010
ISSN: 1936-122X,1936-1238
DOI: 10.1146/annurev.biophys.093008.131348